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GLI1 Antibody

Product Specifications

Background

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

2735

Swiss Prot

P08151

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GLI1 (NP_001153517.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 130kDa/160kDa

Fragment

IgG

Symbol

GLI1

Positive Control 2

Mouse liver

Positive Control 3

Mouse brain

Positive Control 4

Rat brain

NCBI Official Name

GLI family zinc finger 1

NCBI Organism

Homo sapiens

Other Product Names

GLI1, GLI

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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