SP1 Antibody
Product Specifications
Background
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6667
Swiss Prot
P08047
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human SP1 (NP_612482.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
SP1
Positive Control 2
HT-29
Positive Control 3
Mouse thymus
Positive Control 4
Mouse heart
Positive Control 5
Mouse kidney
Positive Control 6
Mouse liver
NCBI Official Name
Sp1 transcription factor
NCBI Organism
Homo sapiens
Other Product Names
SP1, TSFP1
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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