BGLAP Antibody
Product Specifications
Background
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
NCBI Gene ID
632
Swiss Prot
P02818
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGLAP (NP_954642.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-643
Calculated Molecular Weight
Observed: 11kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
BGLAP
Positive Control 2
Mouse pancreas
NCBI Official Name
Bone gamma-carboxyglutamate (gla) protein
NCBI Organism
Homo sapiens
Other Product Names
BGLAP, bone gamma-carboxyglutamate (gla) protein, BGP, OC, OTTHUMP00000016586, bone Gla protein, bone gamma-carboxyglutamate (gla) protein (osteocalcin), gamma-carboxyglutamic acid-containing protein, osteocalcin
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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