MTRR Antibody

Product Specifications

Background

This gene encodes a member of the ferredoxin-NADP (+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

4552

Swiss Prot

Q9UBK8

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_002445.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 80kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MTRR

Positive Control 2

HeLa

Positive Control 3

LO2

Positive Control 4

293T

NCBI Official Name

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

NCBI Organism

Homo sapiens

Other Product Names

MSR, cblE, methionine synthase reductase, [methionine synthase]-cobalamin methyltransferase (cob (II) alamin reducing), methionine synthase reductase, mitochondrial