CDSN Antibody
Product Specifications
Background
This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.
NCBI Gene ID
1041
Swiss Prot
Q15517
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDSN (NP_001255.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
BxPC-3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CDSN
Positive Control 2
A-431
Positive Control 3
NIH/3T3
Positive Control 4
Mouse skin
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Rat skin
NCBI Official Name
Corneodesmosin
NCBI Organism
Homo sapiens
Other Product Names
CDSN, corneodesmosin, D6S586E, HTSS, S, differentiated keratinocyte S protein
Tested Applications
WB
Physical Properties
Liquid
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