CNKSR2 Antibody
Product Specifications
Background
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
22866
Swiss Prot
Q8WXI2
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 117kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CNKSR2
Positive Control 2
Jurkat
Positive Control 3
HepG2
NCBI Official Name
Connector enhancer of kinase suppressor of Ras 2
NCBI Organism
Homo sapiens
Other Product Names
CNK2, KSR2, MAGUIN, MRXSHG, connector enhancer of kinase suppressor of ras 2, CNK homolog protein 2, connector enhancer of KSR2, membrane-associated guanylate kinase-interacting protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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