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DPYSL2 Antibody, KO Validated

Product Specifications

Background

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NCBI Gene ID

1808

Swiss Prot

Q16555

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPYSL2 (NP_001377.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cell Cycle, Neuroscience

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=15-608

Calculated Molecular Weight

Observed: 62kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

DPYSL2

Positive Control 2

U-251MG

Positive Control 3

293T

NCBI Official Name

Dihydropyrimidinase-like 2

NCBI Organism

Homo sapiens

Other Product Names

DPYSL2, CRMP2, CRMP-2, DHPRP2, Dihydropyrimidinase-like 2, DRP-2, N2A3, ULIP2, ULIP-2, Unc-33-like phosphoprotein 2

Tested Applications

WB

Physical Properties

Liquid

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