GSS Antibody, KO Validated
Product Specifications
Background
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
NCBI Gene ID
2937
Swiss Prot
P48637
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 373-474 of human GSS (NP_000169.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GSS
Positive Control 2
K-562
Positive Control 3
293T
Positive Control 4
Mouse kidney
Positive Control 5
Mouse spleen
Positive Control 6
Mouse brain
NCBI Official Name
Glutathione synthetase
NCBI Organism
Homo sapiens
Other Product Names
Glutathione synthetase, GSH synthetase, GSH-S, Glutathione synthase, GSS
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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