AHR Antibody
Product Specifications
Background
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
NCBI Gene ID
196
Swiss Prot
P35869
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR (NP_001612.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Transcription
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 115kDa
Fragment
IgG
Symbol
AHR
Positive Control 2
HepG2
Positive Control 3
293T
Positive Control 4
SW480
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
Aryl hydrocarbon receptor
NCBI Organism
Homo sapiens
Other Product Names
AHR, bHLHe76
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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