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CNR1 Antibody

Product Specifications

Background

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

NCBI Gene ID

1268

Swiss Prot

P21554

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNR1 (NP_001153731.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

Affinity purification

Positive Control

NIH/3T3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 53kDa

Fragment

IgG

Symbol

CNR1

NCBI Official Name

Cannabinoid receptor 1 (brain)

NCBI Organism

Homo sapiens

Other Product Names

Central cannabinoid receptor, cannabinoid receptor 1, CNR, CB1R, CB1K5, CB1A, CB1, CB-R, CANN6, cannabinoid receptor 1 (brain), CNR1

Tested Applications

WB, IHC

Physical Properties

Liquid

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