CNR1 Antibody
Product Specifications
Background
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
NCBI Gene ID
1268
Swiss Prot
P21554
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNR1 (NP_001153731.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 53kDa
Fragment
IgG
Symbol
CNR1
NCBI Official Name
Cannabinoid receptor 1 (brain)
NCBI Organism
Homo sapiens
Other Product Names
Central cannabinoid receptor, cannabinoid receptor 1, CNR, CB1R, CB1K5, CB1A, CB1, CB-R, CANN6, cannabinoid receptor 1 (brain), CNR1
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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