NOL6 Antibody
Product Specifications
Background
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
NCBI Gene ID
65083
Swiss Prot
Q9H6R4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1032-1146 of human NOL6 (NP_075068.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 127kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NOL6
Positive Control 2
A-431
Positive Control 3
HeLa
Positive Control 4
SGC-7901
Positive Control 5
Mouse lung
Positive Control 6
Mouse brain
NCBI Official Name
Nucleolar protein 6 (RNA-associated)
NCBI Organism
Homo sapiens
Other Product Names
NOL6, FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
Tested Applications
WB
Physical Properties
Liquid
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