MRPL15 Antibody
Product Specifications
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
NCBI Gene ID
29088
Swiss Prot
Q9P015
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MRPL15 (NP_054894.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-522
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MRPL15
Positive Control 2
HeLa
Positive Control 3
MCF7
Positive Control 4
A-549
Positive Control 5
Mouse heart
Positive Control 6
Mouse kidney
NCBI Official Name
Mitochondrial ribosomal protein L15
NCBI Organism
Homo sapiens
Other Product Names
HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, 39S ribosomal protein L15, mitochondrial, mitochondrial large ribosomal subunit protein uL15m
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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