CAND1 Antibody
Product Specifications
Background
This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
55832
Swiss Prot
Q86VP6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 750-980 of human CAND1 (NP_060918.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 136kDa
Fragment
IgG
Symbol
CAND1
Positive Control 2
Mouse brain
Positive Control 3
Mouse heart
Positive Control 4
Mouse kidney
Positive Control 5
Mouse liver
Positive Control 6
Rat brain
NCBI Official Name
Cullin-associated and neddylation-dissociated 1
NCBI Organism
Homo sapiens
Other Product Names
TIP120A, TIP120, TIP120A
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
abx334757-01 20 µg
ATP Binding Cassette Subfamily D Member 1 (ABCD1) Antibody (Biotin)
Ask
View Details abx334757-02 50 µg
ATP Binding Cassette Subfamily D Member 1 (ABCD1) Antibody (Biotin)
Ask
View Details