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PTPRG Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

NCBI Gene ID

5793

Swiss Prot

P23470

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human PTPRG (NP_002832.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=15-451

Calculated Molecular Weight

Observed: 140-162kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PTPRG

Positive Control 2

293T

Positive Control 3

Mouse kidney

Positive Control 4

Mouse heart

Positive Control 5

Mouse liver

Positive Control 6

Rat spleen

NCBI Official Name

Protein tyrosine phosphatase, receptor type, G

NCBI Organism

Homo sapiens

Other Product Names

PTPRG, H_RG317H01.1, HPTPG, PTPG, Ptpgamma, RPTPG, PTP gamma, R-PTP-GAMMA

Tested Applications

WB

Physical Properties

Liquid

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