PCDH8 Antibody
Product Specifications
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
NCBI Gene ID
5100
Swiss Prot
O95206
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 450-750 of human PCDH8 (NP_002581.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 113kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PCDH8
Positive Control 2
SH-SY5Y
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
NCBI Official Name
Protocadherin 8
NCBI Organism
Homo sapiens
Other Product Names
PCDH8, ARCADLIN, PAPC
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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