HMGCS2 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3158
Swiss Prot
P54868
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 269-508 of human HMGCS2 (NP_005509.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Symbol
HMGCS2
Positive Control 2
Mouse liver
Positive Control 3
Rat kidney
NCBI Official Name
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
NCBI Organism
Homo sapiens
Other Product Names
HMGCS2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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