MAP2K6 Antibody
Product Specifications
Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
NCBI Gene ID
5608
Swiss Prot
P52564
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MAP2K6 (NP_002749.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Innate Immunity, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MAP2K6
Positive Control 2
Mouse brain
Positive Control 3
Rat brain
NCBI Official Name
Mitogen-activated protein kinase kinase 6
NCBI Organism
Homo sapiens
Other Product Names
MAP2K6, Mapk kinase 6, MAPK/ERK kinase 6, MEK6, SAPKK3, SAPKK-3, MAP kinase kinase 6, MAPKK6, PRKMK6, MAPKK 6, MEK 6, MKK6, SAPK kinase 3, SKK3
Tested Applications
WB
Physical Properties
Liquid
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