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NFATC2 Antibody

Product Specifications

Background

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

NCBI Gene ID

4773

Swiss Prot

Q13469

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2 (NP_775114.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=15-417

Calculated Molecular Weight

Observed: 130kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NFATC2

Positive Control 2

Mouse thymus

Positive Control 3

Mouse spleen

Positive Control 4

Rat liver

NCBI Official Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

NCBI Organism

Homo sapiens

Other Product Names

Nuclear Factor of Activated T Cells; Cytoplasmic 2; NF-ATc2; NF-ATp

Tested Applications

WB

Physical Properties

Liquid

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