NFATC2 Antibody
Product Specifications
Background
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
NCBI Gene ID
4773
Swiss Prot
Q13469
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2 (NP_775114.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 130kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NFATC2
Positive Control 2
Mouse thymus
Positive Control 3
Mouse spleen
Positive Control 4
Rat liver
NCBI Official Name
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NCBI Organism
Homo sapiens
Other Product Names
Nuclear Factor of Activated T Cells; Cytoplasmic 2; NF-ATc2; NF-ATp
Tested Applications
WB
Physical Properties
Liquid
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