NDC80 Antibody
Product Specifications
Background
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
NCBI Gene ID
10403
Swiss Prot
O14777
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human NDC80 (NP_006092.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-371
Calculated Molecular Weight
Observed: 74kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NDC80
Positive Control 2
Lovo
Positive Control 3
MCF7
Positive Control 4
22Rv1
Positive Control 5
THP-1
Positive Control 6
293T
NCBI Official Name
NDC80 kinetochore complex component
NCBI Organism
Homo sapiens
Other Product Names
HEC, highly expressed in cancer, rich in leucine heptad repeats, HEC1, HEC-1, HEC, KNTC2
Tested Applications
WB
Physical Properties
Liquid
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