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CHRNA6 Antibody

Product Specifications

Background

This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.

NCBI Gene ID

8973

Swiss Prot

Q15825

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-440 of human CHRNA6 (NP_004189.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

Raji

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 57kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CHRNA6

Positive Control 2

Rat liver

NCBI Official Name

Cholinergic receptor nicotinic alpha 6 subunit

NCBI Organism

Homo sapiens

Other Product Names

CHNRA6, neuronal acetylcholine receptor subunit alpha-6, acetylcholine receptor, nicotinic, alpha 6 (neuronal), cholinergic receptor, nicotinic alpha 6, cholinergic receptor, nicotinic, alpha 6 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 6

Tested Applications

WB

Physical Properties

Liquid

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