PTS Antibody
Product Specifications
Background
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH (4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
NCBI Gene ID
5805
Swiss Prot
Q03393
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Symbol
PTS
Positive Control 2
U-251MG
Positive Control 3
Mouse kidney
NCBI Official Name
6-pyruvoyltetrahydropterin synthase
NCBI Organism
Homo sapiens
Other Product Names
PTPS, 6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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