KCNJ4 Antibody
Product Specifications
Background
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
3761
Swiss Prot
P48050
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ4 (NP_004972.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 49kDa
Fragment
IgG
Symbol
KCNJ4
Positive Control 2
Mouse skeletal muscle
Positive Control 3
Rat kidney
NCBI Official Name
Potassium inwardly-rectifying channel, subfamily J, member 4
NCBI Organism
Homo sapiens
Other Product Names
KCNJ4, IRK3, Kir2.3, HIR, HIRK2, HRK1, IRK-3, Hippocampal inward rectifier
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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