ITPR1 Antibody

Product Specifications

Background

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

NCBI Gene ID

3708

Swiss Prot

Q14643

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1250 of human ITPR1 (NP_001161744.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 315kDa

Fragment

IgG

Symbol

ITPR1

Positive Control 2

Rat brain

NCBI Official Name

Inositol 1,4,5-trisphosphate receptor, type 1

NCBI Organism

Homo sapiens

Other Product Names

ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, SCA16, Type 1 InsP3 receptor