IFI16 Antibody

Product Specifications

Background

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

3428

Swiss Prot

Q16666

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IFI16 (NP_005522.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Transcription

Purification

Affinity purification

Positive Control

Mouse spleen

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 88kDa

Fragment

IgG

Symbol

IFI16

Positive Control 2

Mouse lung

NCBI Official Name

Interferon gamma inducible protein 16

NCBI Organism

Homo sapiens

Other Product Names

IFNGIP1, PYHIN2, gamma-interferon-inducible protein 16, IFI16 beta isoform, interferon-gamma induced protein IFI 16, interferon-inducible myeloid differentiation transcriptional activator