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GABRA5 Antibody

Product Specifications

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

NCBI Gene ID

2558

Swiss Prot

P31644

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_000801.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

Rat skeletal muscle

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GABRA5

NCBI Official Name

Gamma-aminobutyric acid (GABA) A receptor, alpha 5

NCBI Organism

Homo sapiens

Other Product Names

GABRA5, MGC138184

Tested Applications

WB

Physical Properties

Liquid

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