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SLC25A20 Antibody

Product Specifications

Background

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

NCBI Gene ID

788

Swiss Prot

O43772

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human SLC25A20 (NP_000378.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 39kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SLC25A20

NCBI Official Name

Solute carrier family 25 (carnitine/acylcarnitine translocase), member 20

NCBI Organism

Homo sapiens

Other Product Names

SLC25A20, CAC, CACT

Tested Applications

WB

Physical Properties

Liquid

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