AGER Antibody
Product Specifications
Background
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847) .
NCBI Gene ID
177
Swiss Prot
Q15109
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human AGER (NP_001127.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
AGER
Positive Control 2
NCI-H460
Positive Control 3
Mouse small intestine
Positive Control 4
Rat kidney
NCBI Official Name
Advanced glycosylation end product-specific receptor
NCBI Organism
Homo sapiens
Other Product Names
AGER, MGC22357, RAGE
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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