RhoA Antibody

Product Specifications

Background

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

NCBI Gene ID

387

Swiss Prot

P61586

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 140 to the C-terminus of human RhoA (NP_001655.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

RHOA

NCBI Official Name

Ras homolog family member A

NCBI Organism

Homo sapiens

Other Product Names

RHOA, ARH12, ARHA, Aplysia ras-related homolog 12, H12, Oncogene RHO H12, Rho cDNA clone 12, RHO12, RHOH12, Ras homolog family member A, Small GTP binding protein RhoA, Transforming protein RhoA