PMVK Antibody
Product Specifications
Background
This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
10654
Swiss Prot
Q15126
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human PMVK (NP_006547.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PMVK
Positive Control 2
LO2
Positive Control 3
A-431
Positive Control 4
HeLa
NCBI Official Name
Phosphomevalonate kinase
NCBI Organism
Homo sapiens
Other Product Names
HUMPMKI, PMK, PMKA, PMKASE, POROK1, phosphomevalonate kinase, testis tissue sperm-binding protein Li 95mP
Tested Applications
WB
Physical Properties
Liquid
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