GANAB Antibody

Product Specifications

Background

This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

NCBI Gene ID

23193

Swiss Prot

Q14697

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 112kDa

Fragment

IgG

Symbol

GANAB

Positive Control 2

Raji

Positive Control 3

HepG2

Positive Control 4

HeLa

Positive Control 5

Mouse brain

Positive Control 6

Mouse liver

NCBI Official Name

Glucosidase, alpha; neutral AB

NCBI Organism

Homo sapiens

Other Product Names

GANAB, G2AN, Glucosidase, alpha, Glucosidase, alpha neutral AB, Neutral alpha-glucosidase AB, Alpha-glucosidase 2, Glucosidase II subunit alpha, GLUII, KIAA0088, Neutral AB