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SLC4A10 Antibody

Product Specifications

Background

This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

NCBI Gene ID

57282

Swiss Prot

Q6U841

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 640-725 of human SLC4A10 (NP_001171486.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 180kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SLC4A10

Positive Control 2

Mouse brain

NCBI Official Name

Solute carrier family 4 member 10

NCBI Organism

Homo sapiens

Other Product Names

NBCn2, NCBE, sodium-driven chloride bicarbonate exchanger, solute carrier family 4, sodium bicarbonate cotransporter-like, member 1solute carrier family 4, sodium bicarbonate transporter, member 10

Tested Applications

WB

Physical Properties

Liquid

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