SLC4A10 Antibody
Product Specifications
Background
This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
57282
Swiss Prot
Q6U841
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 640-725 of human SLC4A10 (NP_001171486.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 180kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SLC4A10
Positive Control 2
Mouse brain
NCBI Official Name
Solute carrier family 4 member 10
NCBI Organism
Homo sapiens
Other Product Names
NBCn2, NCBE, sodium-driven chloride bicarbonate exchanger, solute carrier family 4, sodium bicarbonate cotransporter-like, member 1solute carrier family 4, sodium bicarbonate transporter, member 10
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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