IDUA Antibody
Product Specifications
Background
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I) .
NCBI Gene ID
3425
Swiss Prot
P35475
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 354-653 of human IDUA (NP_000194.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IDUA
NCBI Official Name
Iduronidase alpha-L-
NCBI Organism
Homo sapiens
Other Product Names
IDA, MPS1, alpha-L-iduronidase
Tested Applications
WB
Physical Properties
Liquid
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