KARS Antibody
Product Specifications
Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3735
Swiss Prot
Q15046
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human KARS (NP_005539.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 75kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
KARS
Positive Control 2
Jurkat
Positive Control 3
HeLa
Positive Control 4
293T
Positive Control 5
Mouse heart
Positive Control 6
Mouse kidney
NCBI Official Name
Lysyl-tRNA synthetase
NCBI Organism
Homo sapiens
Other Product Names
KARS, KRS, KARS1, KARS2, CMTRIB, DFNB89
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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