MPO Antibody
Product Specifications
Background
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
NCBI Gene ID
4353
Swiss Prot
P05164
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-310 of human MPO (NP_000241.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Innate Immunity
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
MPO
Positive Control 2
HepG2
Positive Control 3
HL-60
Positive Control 4
Mouse pancreas
Positive Control 5
Rat pancreas
NCBI Official Name
Myeloperoxidase
NCBI Organism
Homo sapiens
Other Product Names
MPO, myeloperoxidase
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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