SNUPN Antibody
Product Specifications
Background
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
NCBI Gene ID
10073
Swiss Prot
O95149
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human SNUPN (NP_005692.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 41kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SNUPN
Positive Control 2
HeLa
Positive Control 3
293T
Positive Control 4
Mouse brain
Positive Control 5
Rat brain
NCBI Official Name
Snurportin 1
NCBI Organism
Homo sapiens
Other Product Names
SNUPN, KPNBL, RNUT1, Snurportin1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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