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UBE2L6 Antibody

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

NCBI Gene ID

9246

Swiss Prot

O14933

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human UBE2L6 (NP_004214.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 18kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

UBE2L6

Positive Control 2

Jurkat

Positive Control 3

Mouse kidney

Positive Control 4

Mouse liver

Positive Control 5

Mouse lung

Positive Control 6

Mouse spleen

NCBI Official Name

Ubiquitin-conjugating enzyme E2L 6

NCBI Organism

Homo sapiens

Other Product Names

UBE2L6, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBCH8, RIG-B

Tested Applications

WB

Physical Properties

Liquid

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