UHRF2 Antibody
Product Specifications
Background
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
NCBI Gene ID
115426
Swiss Prot
Q96PU4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 441-622 of human UHRF2 (NP_690856.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Symbol
UHRF2
NCBI Official Name
Ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Other Product Names
UHRF2, NIRF, URF2, RNF107, RP11-472F14.2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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