Eif2ak2 Antibody

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik, interferon-induced, double-stranded RNA-activated protein kinase, IFN- type I-induced and dsRNA-activated kinase, IFN-induced and double-stranded RNA-activated kinase, P1/eIF-2A protein kinase, T-cell viral integration site, dsRNA-activated kinase, eIF-2 alpha, eIF-2A protein kinase 2, interferon-inducible RNA-dependent protein kinase, p68 kinase, protein kinase R, protein kinase RNA-activated, protein kinase, interferon-inducible double stranded RNA dependent, serine/threonine-protein kinase TIK, tyrosine-protein kinase EIF2AK2