PSMA6 Antibody
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.
NCBI Gene ID
5687
Swiss Prot
P60900
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PSMA6 (NP_002782.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-051
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Symbol
PSMA6
Positive Control 2
HeLa
Positive Control 3
A-549
Positive Control 4
COS-7
Positive Control 5
PC-12
Positive Control 6
MCF7
NCBI Official Name
Proteasome (prosome, macropain) subunit, alpha type, 6
NCBI Organism
Homo sapiens
Other Product Names
PSMA6, IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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