LIG3 Antibody
Product Specifications
Background
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
3980
Swiss Prot
P49916
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 730-1009 of human LIG3 (NP_039269.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-032
Calculated Molecular Weight
Observed: 112kDa
Fragment
IgG
Symbol
LIG3
Positive Control 2
BT-474
Positive Control 3
SW480
NCBI Official Name
Ligase III, DNA, ATP-dependent
NCBI Organism
Homo sapiens
Other Product Names
DNA ligase 3, DNA ligase III, LIG2
Tested Applications
WB, IHC
Physical Properties
Liquid
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