LGALS3 Antibody, KO Validated
Product Specifications
Background
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
3958
Swiss Prot
P17931
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-1-250 of human LGALS3 (NP_002297.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 31kDa
Fragment
IgG
Symbol
LGALS3
Positive Control 2
SGC-7901
Positive Control 3
HeLa
Positive Control 4
Mouse brain
Positive Control 5
Mouse kidney
NCBI Official Name
Lectin, galactoside-binding, soluble, 3
NCBI Organism
Homo sapiens
Other Product Names
L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, Galectin-3, 35 kDa lectin, Gal-3
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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