RAD18 Antibody
Product Specifications
Background
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
NCBI Gene ID
56852
Swiss Prot
Q9NS91
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human RAD18 (NP_064550.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Symbol
RAD18
Positive Control 2
MCF7
Positive Control 3
Jurkat
Positive Control 4
293T
Positive Control 5
Mouse liver
NCBI Official Name
RAD18 homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Other Product Names
RAD18, RNF73
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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