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YWHAZ Antibody

Product Specifications

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

NCBI Gene ID

7534

Swiss Prot

P63104

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human YWHAZ (NP_001129171.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Symbol

YWHAZ

Positive Control 2

HeLa

Positive Control 3

A-549

Positive Control 4

MCF7

Positive Control 5

Mouse brain

Positive Control 6

Mouse lung

NCBI Official Name

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

NCBI Organism

Homo sapiens

Other Product Names

YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta

Tested Applications

WB, IF

Physical Properties

Liquid

Frequently Asked Questions

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