YWHAZ Antibody
Product Specifications
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
NCBI Gene ID
7534
Swiss Prot
P63104
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human YWHAZ (NP_001129171.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 28kDa
Fragment
IgG
Symbol
YWHAZ
Positive Control 2
HeLa
Positive Control 3
A-549
Positive Control 4
MCF7
Positive Control 5
Mouse brain
Positive Control 6
Mouse lung
NCBI Official Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
NCBI Organism
Homo sapiens
Other Product Names
YWHAZ, KCIP-1, MGC111427, MGC126532, MGC138156, HEL4, YWHAD, HEL-S-3, 14-3-3-zeta
Tested Applications
WB, IF
Physical Properties
Liquid
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