What is the catalog number for MDM2 Antibody?

The catalog number for MDM2 Antibody is 14-921.

What sizes are available for MDM2 Antibody?

MDM2 Antibody is available in the following size(s): 100 µL.

Is MDM2 Antibody in stock?

MDM2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MDM2 Antibody

Product Specifications

Background

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

NCBI Gene ID

4193

Swiss Prot

Q00987

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-430 of human MDM2 (NP_002383.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 52kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MDM2

Positive Control 2

SKOV3

Positive Control 3

MCF7

Positive Control 4

Mouse thymus

Positive Control 5

Mouse lung

NCBI Official Name

MDM2 oncogene, E3 ubiquitin protein ligase

NCBI Organism

Homo sapiens

Other Product Names

MDM2, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse), HGNC:6973, MGC71221, hdm2, mouse double minute 2 homolog, mouse double minute 2, human homolog of, p53-binding protein, p53-binding protein MDM2, ubiquitin-protein ligase E3 Mdm2, HDMX, ACTFS