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DSP Antibody

Product Specifications

Background

This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

1832

Swiss Prot

P15924

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 2750-2850 of human DSP (NP_004406.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=14-900

Calculated Molecular Weight

Observed: 315kDa

Fragment

IgG

Symbol

DSP

NCBI Official Name

Desmoplakin

NCBI Organism

Homo sapiens

Other Product Names

DSP, DPI, desmoplakin I, desmoplakin, 250kDa paraneoplastic pemphigus antigen, DP, DPII

Tested Applications

WB, IHC

Physical Properties

Liquid

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