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LRAT Antibody

Product Specifications

Background

The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

9227

Swiss Prot

O95237

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human LRAT (NP_004735.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse lung

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 26-55kDa

Fragment

IgG

Symbol

LRAT

Positive Control 2

Rat small intestine

NCBI Official Name

Lecithin retinol acyltransferase

NCBI Organism

Homo sapiens

Other Product Names

LCA14, lecithin retinol acyltransferase, lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)

Tested Applications

WB, IF

Physical Properties

Liquid

Frequently Asked Questions

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