PON1 Antibody
Product Specifications
Background
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
NCBI Gene ID
5444
Swiss Prot
P27169
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 9-109 of human PON1 (NP_000437.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PON1
Positive Control 2
NCI-H460
Positive Control 3
HT-1080
Positive Control 4
THP-1
Positive Control 5
Mouse kidney
Positive Control 6
Rat kidney
NCBI Official Name
Paraoxonase 1
NCBI Organism
Homo sapiens
Other Product Names
PON1, ESA, PON, MVCD5
Tested Applications
WB
Physical Properties
Liquid
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