TDO2 Antibody
Product Specifications
Background
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
NCBI Gene ID
6999
Swiss Prot
P48775
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-260 of human TDO2 (NP_005642.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TDO2
Positive Control 2
Mouse liver
Positive Control 3
Mouse kidney
Positive Control 4
Mouse small intestine
Positive Control 5
Rat liver
NCBI Official Name
Tryptophan 2,3-dioxygenase
NCBI Organism
Homo sapiens
Other Product Names
TDO2, TDO, TPH2, TRPO, TO
Tested Applications
WB
Physical Properties
Liquid
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