U2AF1 Antibody
Product Specifications
Background
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
7307
Swiss Prot
Q01081
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human U2AF1 (NP_006749.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-831
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Symbol
U2AF1
Positive Control 2
HeLa
Positive Control 3
K-562
Positive Control 4
LO2
Positive Control 5
Mouse spleen
Positive Control 6
Mouse kidney
NCBI Official Name
Splicing factor U2AF 35 kDa subunit
NCBI Organism
Homo sapiens
Other Product Names
Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit, U2AF1, U2AF35, U2AFBP
Tested Applications
WB, IHC
Physical Properties
Liquid
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