PRDM2 Antibody
Product Specifications
Background
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
7799
Swiss Prot
Q13029
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PRDM2 (NP_036363.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-825
Calculated Molecular Weight
Observed: 300kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PRDM2
Positive Control 2
LO2
Positive Control 3
MCF7
Positive Control 4
Mouse brain
Positive Control 5
Mouse liver
Positive Control 6
Rat brain
NCBI Official Name
PR/SET domain 2
NCBI Organism
Homo sapiens
Other Product Names
HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain zinc finger protein 2, GATA-3 binding protein G3B, MTE-binding protein, PR domain 2, PR domain containing 2, with ZNF domain, PR domain-containing protein 2, lysine N-methyltransferase 8, retinoblastoma protein-binding zinc finger protein, retinoblastoma protein-interacting zinc finger protein, zinc finger protein RIZ, zinc-finger DNA-binding protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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